White-to-brite conversion in human adipocytes promotes metabolic reprogramming towards fatty acid anabolic and catabolic pathways - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Molecular metabolism Année : 2016

White-to-brite conversion in human adipocytes promotes metabolic reprogramming towards fatty acid anabolic and catabolic pathways

Résumé

Fat depots with thermogenic activity have been identified in humans. In mice, the appearance of thermogenic adipocytes within white adipose depots (so-called brown-in-white i.e., brite or beige adipocytes) protects from obesity and insulin resistance. Brite adipocytes may originate from direct conversion of white adipocytes. The purpose of this work was to characterize the metabolism of human brite adipocytes.
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hal-02134884 , version 1 (27-05-2020)

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V Barquissau, D. Beuzelin, D. Pisani, G.E. Beranger, A. Mairal, et al.. White-to-brite conversion in human adipocytes promotes metabolic reprogramming towards fatty acid anabolic and catabolic pathways. Molecular metabolism, 2016, 5 (5), pp.352-365. ⟨10.1016/j.molmet.2016.03.002⟩. ⟨hal-02134884⟩
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