Novel constrained CCK-B dipeptoid antagonists derived from pipecolic acid. - Archive ouverte HAL
Article Dans Une Revue Bioorganic and Medicinal Chemistry Letters Année : 1998

Novel constrained CCK-B dipeptoid antagonists derived from pipecolic acid.

S da Nascimento
  • Fonction : Auteur
H. Meudal
E. Gincel
  • Fonction : Auteur
B.P Roques
  • Fonction : Auteur
C Garbay

Résumé

A new series of 4-substituted pipecolic acid derivatives was prepared and incorporated into dipeptoids. The resulting products behave as moderately potent CCK-B antagonists but their constrained structure and its comparison with structurally related compounds yield valuable information about the conformational requirements for optimal recognition of the CCK-B receptor by antagonists.
Fichier non déposé

Dates et versions

hal-02122133 , version 1 (07-05-2019)

Identifiants

  • HAL Id : hal-02122133 , version 1
  • PUBMED : 9871777

Citer

B Bellier, S da Nascimento, H. Meudal, E. Gincel, B.P Roques, et al.. Novel constrained CCK-B dipeptoid antagonists derived from pipecolic acid.. Bioorganic and Medicinal Chemistry Letters, 1998, 8 (11), pp.1419-24. ⟨hal-02122133⟩
18 Consultations
0 Téléchargements

Altmetric

Partager

More