[Ala4]surfactin, a novel isoform from Bacillus subtilis studied by mass and NMR spectroscopies. - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue European Journal of Biochemistry Année : 1994

[Ala4]surfactin, a novel isoform from Bacillus subtilis studied by mass and NMR spectroscopies.

M Peypoux
  • Fonction : Auteur
J.M Bonmatin
H Labbe
  • Fonction : Auteur
G Grangemard
  • Fonction : Auteur
B Das
  • Fonction : Auteur
J. Wallach
  • Fonction : Auteur
G. Michel
  • Fonction : Auteur

Résumé

When Bacillus subtilis S 499 was grown on a culture medium containing L-alanine as nitrogen source, a mixture of surfactins was obtained. Suitable chromatographic conditions allowed the separation of isoforms. Among these compounds, a new variant of surfactin was isolated and its structure was established by chemical and spectrometric methods, especially by NMR spectrometry. It contains a peptide sequence which differs from that of standard surfactin by the replacement of the L-valine residue by L-alanine residue in position 4. The folding mode of [Ala4]surfactin as deduced from NMR results was compared with that of standard surfactin and the structure/properties relationship issuing from the study of this new isoform is discussed.
Fichier non déposé

Dates et versions

hal-02082597 , version 1 (28-03-2019)

Identifiants

  • HAL Id : hal-02082597 , version 1
  • PUBMED : 8076655

Citer

M Peypoux, J.M Bonmatin, H Labbe, G Grangemard, B Das, et al.. [Ala4]surfactin, a novel isoform from Bacillus subtilis studied by mass and NMR spectroscopies.. European Journal of Biochemistry, 1994, 224 (1), pp.89-96. ⟨hal-02082597⟩
9 Consultations
0 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More