Salvage Debridement, Antibiotics and Implant Retention ("DAIR") With Local Injection of a Selected Cocktail of Bacteriophages: Is It an Option for an Elderly Patient With Relapsing Staphylococcus aureus Prosthetic-Joint Infection? - Archive ouverte HAL Access content directly
Journal Articles Open Forum Infectious Diseases Year : 2018

Salvage Debridement, Antibiotics and Implant Retention ("DAIR") With Local Injection of a Selected Cocktail of Bacteriophages: Is It an Option for an Elderly Patient With Relapsing Staphylococcus aureus Prosthetic-Joint Infection?

Cindy Fevre
  • Function : Author
Mathieu Medina
  • Function : Author
The Lyon Bji Study Group
  • Function : Author

Abstract

Local injection of a bacteriophages mix during debridement, antibiotics and implant retention ("DAIR") was performed to treat a relapsing Staphylococcus aureus chronic prosthetic joint infection (PJI). This salvage treatment was safe and associated with a clinical success. Scientific evaluation of the potential clinical benefit of bacteriophages as antibiofilm treatment in PJI is now feasible and required.

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Imaging

Dates and versions

hal-02076758 , version 1 (22-03-2019)

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Tristan Ferry, Gilles Leboucher, Cindy Fevre, Yannick Herry, Anne Conrad, et al.. Salvage Debridement, Antibiotics and Implant Retention ("DAIR") With Local Injection of a Selected Cocktail of Bacteriophages: Is It an Option for an Elderly Patient With Relapsing Staphylococcus aureus Prosthetic-Joint Infection?. Open Forum Infectious Diseases, 2018, 5 (11), pp.ofy269. ⟨10.1093/ofid/ofy269⟩. ⟨hal-02076758⟩
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