Journal Articles Open Forum Infectious Diseases Year : 2018

Salvage Debridement, Antibiotics and Implant Retention ("DAIR") With Local Injection of a Selected Cocktail of Bacteriophages: Is It an Option for an Elderly Patient With Relapsing Staphylococcus aureus Prosthetic-Joint Infection?

Abstract

Local injection of a bacteriophages mix during debridement, antibiotics and implant retention ("DAIR") was performed to treat a relapsing Staphylococcus aureus chronic prosthetic joint infection (PJI). This salvage treatment was safe and associated with a clinical success. Scientific evaluation of the potential clinical benefit of bacteriophages as antibiofilm treatment in PJI is now feasible and required.

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Infectious diseases Biotechnology Rhumatology and musculoskeletal system
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https://hal.science/hal-02076758

Submitted on : Monday, January 6, 2025-2:45:11 PM

Last modification on : Thursday, January 9, 2025-11:49:20 AM

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hal-02076758 , version 1 (06-01-2025)

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Tristan Ferry, Gilles Leboucher, Cindy Fevre, Yannick Herry, Anne Conrad, et al.. Salvage Debridement, Antibiotics and Implant Retention ("DAIR") With Local Injection of a Selected Cocktail of Bacteriophages: Is It an Option for an Elderly Patient With Relapsing Staphylococcus aureus Prosthetic-Joint Infection?. Open Forum Infectious Diseases, 2018, 5 (11), pp.ofy269. ⟨10.1093/ofid/ofy269⟩. ⟨hal-02076758⟩

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UNIV-ST-ETIENNE ENS-LYON HCL UGA CNRS UNIV-LYON1 CIRI LBMC UDL CIRI-P-DOUBLET-S-JARRAUD-LEGIOPATH CIRI-F-VANDENESCH-STAPATH
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