The wine industry has been confronted with changing issues over time, but has proved able to adapt, becoming the second-largest contributor to the French trade balance. Strategies have been put in place in wine regions to ensure vineyards’ sustainability or emergence. In order to examine these strategies in greater detail, we focus in this article on a peri-urban wine region (the vineyards of the Vouvray protected designation of origin), which faces different issues, in particular the pressure exerted by the growth of a nearby urban area – now considered as métropole or “metropolis” in administrative terms – namely Tours, in the Loire Valley in west-central France. How can these vineyards be maintained spatially in the face of other types of land use with more immediate economic and financial benefits? How can the area preserve its identity without missing out on the advances and opportunities of modernity? An analysis of the landscape dynamics at play shows that the threat of urbanization is more a fear than a reality, but only because the Vouvray vineyards have resisted relatively successfully. First, they adapted their production, by focusing on quality. They now also benefit from a new context, which elevates these vineyards to the rank of spaces with high heritage and landscape value. The case study of Vouvray shows that these peri-urban vineyards lie at the heart of multiple stakes and challenges, involving many actors and a “nesting” of scales, from the local to the global. To continue to survive, the vineyards must adapt, taking into account this pluralistic context. They must take advantage of favorable elements of this context (increased interest in landscapes and wine heritage, development of wine tourism, desire for higher-quality products) in order to enhance their value and deflect threats (urbanization, competition from new wines).