BLOCK DESIGNS FOR EARLY-STAGE CLINICAL TRIALS
Résumé
We provide a commented list of uniform on periods incomplete block designs appropriate for early-stage clinical trials. The optimality of these designs with respect to the NN1 and NN2 nearest-neighbour correlation models studied by Kiefer and Wynn (1981) and Morgan and Chakravarti (1988) is discussed.
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Block Designs for Early Stage Clinical Trials.pdf (254.16 Ko)
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