Reducing PEC uncertainty in coastal zones: a case study on carbamazepine, oxcarbazepine and their metabolites. - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Environment International Année : 2014

Reducing PEC uncertainty in coastal zones: a case study on carbamazepine, oxcarbazepine and their metabolites.

L. Arpin-Pont
  • Fonction : Auteur
  • PersonId : 1310671
  • IdRef : 200493779
D. Munaron
  • Fonction : Auteur
A. Fiandrino
  • Fonction : Auteur
E. Gomez

Résumé

Concentrations of the antiepileptic drugs carbamazepine (Cbz), oxcarbazepine (OxCz) and their main metabolites were predicted in a wastewater treatment plant (WTP) and in the vicinity of its submarine outfall located in a Mediterranean coastal zone. Refined predicted environmental concentrations (PECs) were calculated in effluents based on consumption data and human excretion rates. PECs were estimated in the sea using the hydrodynamic MARS 3D model integrating meteorological data, oceanic conditions (wind, tide, atmospheric pressure), freshwater and sewage inputs. Measured environmental concentrations (MECs) were compared to PECs to assess the estimation relevance. In the coastal zone, PEC and MEC were in the same magnitude range. Modeling of Cbz diffusion and advection just above the submarine outfall showed the influence of the thermocline during summer, with low diffusion of Cbz from the bottom to the surface. This work allowed understanding the dispersion of target compounds and deserved further development for a better acknowledgement of vulnerability at local scales.

Domaines

Hydrologie
Fichier non déposé

Dates et versions

hal-02049014 , version 1 (26-02-2019)

Identifiants

Citer

H. Fenet, L. Arpin-Pont, A. Vanhoutte-Brunier, D. Munaron, A. Fiandrino, et al.. Reducing PEC uncertainty in coastal zones: a case study on carbamazepine, oxcarbazepine and their metabolites.. Environment International, 2014, 68, pp.177--184. ⟨10.1016/j.envint.2014.03.025⟩. ⟨hal-02049014⟩
43 Consultations
0 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More