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Article Dans Une Revue Metallomics Année : 2014

Use of a new water-soluble Zn sensor to determine Zn affinity for the amyloid-b peptide and relevant mutants

Résumé

Evaluation of Zn affinity for the amyloid-[small beta] peptide involved in Alzheimer's disease and its modified counterparts is reported. This was made possible by the use of a new water-soluble chelator, the properties of which have also been described. Changes in the peptide sequence that impact Zn affinity are briefly discussed.

Dates et versions

hal-02023148 , version 1 (18-02-2019)

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Sabrina Noël, S. Bustos Rodriguez, S. Sayen, E. Guillon, Peter Faller, et al.. Use of a new water-soluble Zn sensor to determine Zn affinity for the amyloid-b peptide and relevant mutants. Metallomics, 2014, 6 (7), pp.1220-1222. ⟨10.1039/C4MT00016A⟩. ⟨hal-02023148⟩
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