1-Butanol (or biobutanol) was recently proposed to be used with gasoline, and engine tests were performed. However, only few studies concern the oxidation/combustion of 1-butanol and they do not provide directly usable data for kinetic modeling. Thus the oxidation of butanol-gasoline surrogate mixtures (85%-15% vol.) was studied using a jet stirred reactor. One representative of the chemical classes constituting this fuel was selected. These constituents were iso-octane, toluene, 1-hexene and 1-butanol. The experiments were carried out in the temperature range 770-1220 K, at 10 atm, with an initial fuel concentration of 0.1% in mole. Four equivalence ratios were considered: 0.3, 0.6, 1, and 2. Concentration profiles of reactants, stable intermediates, and final products were measured via sonic probe sampling followed by FTIR and gas chromatography analyses. A detailed chemical kinetic scheme (251 species, 1990 reversible reactions) resulting from the merging of validated kinetic schemes for the oxidation of the pure components of the present butanol-gasoline surrogate was used to simulate the present experiments. Good agreement between the experimental results and the computations was observed under the present JSR conditions.