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Article Dans Une Revue Heterocycles Année : 2018

Towards New Sila- or Germa-Derivatives of Motesanib

Résumé

Developing new access to original silylated heterocycles is an emerging challenge in medicinal chemistry. In this paper, we describe a synthesis of silylated and germylated Motesanib analogues relying on a peptide coupling between a nicotinic acid derivative and silylated or germylated heterocycles, prepared according to our previous reports.

Domaines

Chimie organique
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Dates et versions

hal-02019339 , version 1 (14-02-2019)

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Thomas Boddaert, Olivier Querolle, Lieven Meerpoel, Patrick Angibaud, Jacques Maddaluno, et al.. Towards New Sila- or Germa-Derivatives of Motesanib. Heterocycles, 2018, 97 (2), pp.1210-1218. ⟨10.3987/COM-18-S(T)70⟩. ⟨hal-02019339⟩
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