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Article Dans Une Revue Angewandte Chemie International Edition Année : 2017

Oxidative Neutralization of Mustard-Gas Simulants in an On-Board Flow Device with In-Line NMR Monitoring

Résumé

The fast and effective neutralization of the mustard‐gas simulant 2‐chloroethyl ethyl sulfide (CEES) using a simple and portable continuous flow device is reported. Neutralization takes place through a fully selective sulfoxidation by a stable source of hydrogen peroxide (alcoholic solution of urea–H2O2 adduct/MeSO3H freshly prepared). The reaction progress can be monitored with an in‐line benchtop NMR spectrometer, allowing a real‐time adjustment of reaction conditions. Inherent features of millireactors, that is, perfect control of mixing, heat and reaction time, allowed the neutralization of 25 g of pure CEES within 46 minutes in a 21.5 mL millireactor (tR=3.9 minutes). This device, which relies on affordable and nontoxic reagents, fits into a suitcase, and can be deployed by police/military forces directly on the attack site.

Domaines

Chimie organique
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Dates et versions

hal-02019160 , version 1 (14-02-2019)

Identifiants

Citer

Baptiste Picard, Boris Gouilleux, Thomas Lebleu, Jacques Maddaluno, Isabelle Chataigner, et al.. Oxidative Neutralization of Mustard-Gas Simulants in an On-Board Flow Device with In-Line NMR Monitoring. Angewandte Chemie International Edition, 2017, 56 (26), pp.7568-7572. ⟨10.1002/anie.201702744⟩. ⟨hal-02019160⟩
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