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Article Dans Une Revue Journal of Organic Chemistry Année : 2017

Cobalt-Catalyzed Carbozincation of Ynamides

Résumé

An original cobalt-catalyzed ynamide carbozincation leading mainly to diverse 3-aryl enamides with mild reaction conditions and good functional-group tolerance has been developed. This reaction displays an excellent regio- and total stereoselectivity and opens the way to appealing synthetic applications. Moreover, this approach allows the selective synthesis of biologically relevant 3,5-disubstituted oxazolone frameworks.

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Autre
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Dates et versions

hal-01999912 , version 1 (30-01-2019)

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Romain Sallio, Martin Corpet, Loic Habert, Muriel Durandetti, Corinne Gosmini, et al.. Cobalt-Catalyzed Carbozincation of Ynamides. Journal of Organic Chemistry, 2017, 82 (2), pp.1254-1259. ⟨10.1021/acs.joc.6b02612⟩. ⟨hal-01999912⟩
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