A simple thermodynamic closure for the simulation of multiphase reactive flows is presented. It combines a fully explicit thermodynamic closure appropriate for weakly thermal multiphase flow simulations, with the classical variable heat capacity ideal gas thermodynamic closure, commonly used for reactive flows simulations. Each liquid and gas component is assumed to follow the recent Noble-Abel Stiffened Gas equation of state, fully described by a set of five parameters. A new method for setting these parameters is presented and validated through comparisons with NIST references. Comparisons with a well-known cubic equation of state, Soave-Redlich-Kwong, are also included. The Noble-Abel Stiffened-Gas equation of state is then extended as to cope with variable heat capacity, to make the mixture ther-modynamic closure appropriate for multiphase reactive flows.