Fast compressive Raman bio-imaging via matrix completion - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Optica Année : 2019

Fast compressive Raman bio-imaging via matrix completion

Résumé

Raman microscopy is a powerful method combining non-invasiveness with no special sample preparation. Because of this remarkable simplicity, it has been widely exploited in many fields, ranging from life and materials sciences, to engineering. Notoriously, due to the required imaging speeds for bio-imaging, it has remained a challenge how to use this technique for dynamic and large-scale imaging. Recently, compressive Raman has been put forward, allowing for fast imaging, therefore solving the issue of speed. Yet, due to the need of strong a priori information of the species forming the hyperspectrum, it has remained elusive how to apply this technique for microspectroscopy of (dynamic) biological tissues. Combining an original spectral under-sampling measurement technique with matrix completion framework for reconstruction, we demonstrate fast and inexpensive label-free molecular imaging of biological specimens (brain tissues and single cells). Therefore, our results open interesting perspectives for clinical and cell biology applications using the much faster compressive Raman framework.

Dates et versions

hal-01960319 , version 1 (19-12-2018)

Identifiants

Citer

Fernando Soldevila, Jonathan Dong, Enrique Tajahuerce, Sylvain Gigan, Hilton B. de Aguiar. Fast compressive Raman bio-imaging via matrix completion. Optica, 2019, 6, pp.341-346. ⟨10.1364/OPTICA.6.000341⟩. ⟨hal-01960319⟩
150 Consultations
0 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More