Effect of spectrin network elasticity on the shapes of erythrocyte doublets - Archive ouverte HAL
Article Dans Une Revue Soft Matter Année : 2018

Effect of spectrin network elasticity on the shapes of erythrocyte doublets

Résumé

Red blood cell (RBC) aggregates play an important role in determining blood rheology. RBCs in plasma or polymer solution interact attractively to form various shapes of RBC doublets, where the attractive interactions can be varied by changing the solution conditions. A systematic numerical study on RBC doublet formation is performed, which takes into account the shear elasticity of the RBC membrane due to the spectrin cytoskeleton, in addition to the membrane bending rigidity. RBC membranes are modeled by two-dimensional triangulated surfaces embedded into three dimensions. The phase space of RBC doublet shapes in a wide range of adhesion strengths, reduced volumes, and shear elasticities is obtained. The shear elasticity of the RBC membrane changes the doublet phases significantly. Experimental images of RBC doublets in different solutions show similar configurations. Furthermore, we show that rouleau formation is affected by the doublet structure.
Fichier principal
Vignette du fichier
Spectrin_doublets2.pdf (3.14 Mo) Télécharger le fichier
Origine Fichiers produits par l'(les) auteur(s)

Dates et versions

hal-01957847 , version 1 (16-11-2020)

Identifiants

Citer

Masoud Hoore, François Yaya, Thomas Podgorski, Christian Wagner, Gerhard Gompper, et al.. Effect of spectrin network elasticity on the shapes of erythrocyte doublets. Soft Matter, 2018, 14 (30), pp.6278-6289. ⟨10.1039/c8sm00634b⟩. ⟨hal-01957847⟩
65 Consultations
79 Téléchargements

Altmetric

Partager

More