Mystery solved: VSV-G-LVs do not allow efficient gene transfer into unstimulated T cells, B cells, and HSCs because they lack the LDL receptor
Mots clés
B-Lymphocytes
Cells
Cultured
Genetic Therapy
Genetic Vectors
Hematopoietic Stem Cell Transplantation
Hematopoietic Stem Cells
Humans
Immunotherapy
Active
Lentivirus
Lymphocyte Activation
Membrane Glycoproteins
Receptors
LDL
T-Lymphocytes
Transduction
Genetic
Treatment Failure
Viral Envelope Proteins
Virus Internalization