Web based e-Education systems are an important kind of information systems that benefited from Web standards for implementation, deployment and integration. In this paper we propose and evaluate a semantic Web approach to support the features and interoperability of a real industrial e-Education system in production. We show how ontology-based knowledge representation supports the required features, their extension to new ones and the integration of external resources (e.g. official standards) as well as the interoperability with other systems. We designed and implemented a proof of concept in an industrial context that was qualitatively and quantitatively evaluated and we benchmarked different alternatives on real data and real queries. We present a complete evaluation of the quality of service and response time in this industrial context and we show that on a real-world tesbed Semantic Web based solutions can meet the industrial requirements, both in terms of functionalities and efficiency compared to existing operational solutions. We also show that an ontology-oriented modelling opens up new opportunities of advanced functionalities supporting resource recommendation and adaptive learning.