Tropheryma whipplei Increases Expression of Human Leukocyte Antigen-G on Monocytes to Reduce Tumor Necrosis Factor and Promote Bacterial Replication - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Gastroenterology Année : 2018

Tropheryma whipplei Increases Expression of Human Leukocyte Antigen-G on Monocytes to Reduce Tumor Necrosis Factor and Promote Bacterial Replication

Résumé

Infection with Tropheryma whipplei has a range of effects-some patients can be chronic carriers without developing any symptoms whereas others can develop systemic Whipple disease, characterized by a lack a protective inflammatory immune response. Alterations in major histocompatibility complex, class I, G (HLA-G) function have been associated with several diseases. We investigated the role of HLA-G during T whipplei infection.
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hal-01869370 , version 1 (06-09-2018)

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Eya Ben Azzouz, Asma Boumaza, Soraya Mezouar, Matthieu Bardou, Federico Carlini, et al.. Tropheryma whipplei Increases Expression of Human Leukocyte Antigen-G on Monocytes to Reduce Tumor Necrosis Factor and Promote Bacterial Replication. Gastroenterology, 2018, 155 (5), pp.1553-1563. ⟨10.1053/j.gastro.2018.07.034⟩. ⟨hal-01869370⟩
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