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Article Dans Une Revue PROJECT PERSPECTIVES Année : 2012

Decision-making under uncertainty in drug development

Résumé

In pharmaceutical industry, decision-makers have to decide whether to continue drug development projects, if the tests results on new compounds are good enough. Such decisions are made collectively , under a high degree of uncertainty and in non-emergency situations. These projects are very expensive, risky, and long. The major problem in this context is indecision. In order to improve the decision-making process in practice, we need to characterize and analyze situations of decision-making under uncertainty. In this paper, we propose a new defi nition of uncertainty that takes human factors in its characterization into account. Then, the factors that contribute to generate, characterize, perceive or process uncertainty are structured in a typology. That helps us recognize and explore causal and infl uential factors of uncertainty. Additionally, based on interview results, we present a description of the decision-making process in pharmaceutical R&D, illustrating the role of different actors, their interactions, and the fl ow of information. This should help decision-makers adopt proactive practices instead of reactive ones.
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Dates et versions

hal-01847754 , version 1 (07-11-2018)

Identifiants

  • HAL Id : hal-01847754 , version 1

Citer

Saïna Hassanzadeh, Didier Gourc, François Marmier, Sophie Bougaret. Decision-making under uncertainty in drug development. PROJECT PERSPECTIVES, 2012, 34, p.40-45. ⟨hal-01847754⟩
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