Radical allylation: (E)-selective radical conjugate addition-elimination reaction from Morita-Baylis-Hillman adducts
Résumé
Triethylborane-mediated radical allylation was performed from Morita–Baylis–Hillman alcohols with no need of protecting group. The radical conjugated addition–elimination reaction is highly selective, and trisubstituted E-alkenes were obtained. This reaction opened a new route for the preparation of functionalized α,β-unsaturated ketones.