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Article Dans Une Revue Tetrahedron Année : 2016

Easy solventless synthesis of new mono and bis amino-5H-chromeno [3,4-c] pyridin-5-one derivatives

Résumé

A new series of mono and bis amino-5H-chromeno [3,4-c] pyridin-5-one derivatives were prepared via the reaction of primary amines with 4-(2-(dimethylamino)vinyl)-2-oxo-2H-chromene-3-carbonitrile 3. The X-rays structures of 4-(hexylamino)-5H-chromeno[3.4-c]pyridin-5-one 4a are reported and discussed. The proposed synthesis method provides several advantages including a simple chemistry handling, mild reaction conditions and an environmentally friendly synthesis pathway.
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hal-01829058 , version 1 (03-07-2018)

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Zahira Kibou, Didier Villemin, Jean-François Lohier, Nawel Cheikh, Nathalie Bar, et al.. Easy solventless synthesis of new mono and bis amino-5H-chromeno [3,4-c] pyridin-5-one derivatives. Tetrahedron, 2016, 72 (13), pp.1653 - 1661. ⟨10.1016/j.tet.2016.01.063⟩. ⟨hal-01829058⟩
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