Hepatitis A: an epidemiological survey in blood donors, France 2015 to 2017
Résumé
Since mid-2016, hepatitis A virus (HAV) outbreaks, involving predominantly men who have sex with men (MSM), have affected countries in Europe and overseas. In France, HAV screening of blood donations in 2017 revealed a HAV-RNA prevalence ca fivefold higher than during 2015-16 (4.42/106 vs 0.86/106; p = 0.0005). In 2017, despite a higher male-to-female ratio (5.5 vs 0.7) and the identification of MSM-associated outbreak strains, only one of 11 infected male donors self-reported being a MSM. Since mid-2016, outbreaks involving mainly men who have sex with men (MSM) have been reported in European countries and overseas [1-6]. The outbreaks were associated with three genotype IA hepatitis A virus (HAV) strains: VDR_521_2016, RIVM_HAV16-090 and V16-25801. In this study, we report epidemiological and clinical findings pertaining to HAV infected blood donors before and during the recent outbreak in France.
Mots clés
2 Unité des Virus Emergents (UVE: Aix-Marseille Univ -IRD 190 -Inserm 1207 -IHU Méditerranée Infection)
Marseille
France 3 Etablissement Français du Sang Auvergne Rhône Alpes
Beynost
France 4 AP-HP
Hôpital Paul Brousse
Virologie
CNR des Virus des hépatites à transmission entérique
INSERM U1993
Villejuif
France 5 Etablissement Français du Sang
Saint Denis-La
Domaines
Sciences du Vivant [q-bio]
Origine : Publication financée par une institution
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