This article discusses MLMC estimators with and without weights, applied to nested expectations of the form E [f (E [F (Y, Z)|Y ])]. More precisely, we are interested on the assumptions needed to comply with the MLMC framework, depending on whether the payoff function f is smooth or not. A new result to our knowledge is given when f is not smooth in the development of the weak error at an order higher than 1, which is needed for a successful use of MLMC estimators with weights.