<?xml version="1.0" encoding="utf-8"?>
<TEI xmlns="http://www.tei-c.org/ns/1.0" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:hal="http://hal.archives-ouvertes.fr/" xmlns:gml="http://www.opengis.net/gml/3.3/" xmlns:gmlce="http://www.opengis.net/gml/3.3/ce" version="1.1" xsi:schemaLocation="http://www.tei-c.org/ns/1.0 http://api.archives-ouvertes.fr/documents/aofr-sword.xsd">
  <teiHeader>
    <fileDesc>
      <titleStmt>
        <title>HAL TEI export of hal-01816598</title>
      </titleStmt>
      <publicationStmt>
        <distributor>CCSD</distributor>
        <availability status="restricted">
          <licence target="https://creativecommons.org/publicdomain/zero/1.0/">CC0 1.0 - Universal</licence>
        </availability>
        <date when="2026-05-19T01:54:37+02:00"/>
      </publicationStmt>
      <sourceDesc>
        <p part="N">HAL API Platform</p>
      </sourceDesc>
    </fileDesc>
  </teiHeader>
  <text>
    <body>
      <listBibl>
        <biblFull>
          <titleStmt>
            <title xml:lang="en">DNA Self-Assembly: From Chirality to Evolution</title>
            <author role="aut">
              <persName>
                <forename type="first">Y.</forename>
                <surname>Timsit</surname>
              </persName>
              <email type="md5">8345a2ed975ba3439a75140c84785620</email>
              <email type="domain">mio.osupytheas.fr</email>
              <idno type="idhal" notation="string">youri-timsit</idno>
              <idno type="idhal" notation="numeric">20065</idno>
              <idno type="halauthorid" notation="string">3482-20065</idno>
              <idno type="ORCID">https://orcid.org/0000-0003-0601-7201</idno>
              <idno type="IDREF">https://www.idref.fr/263483835</idno>
              <idno type="VIAF">https://viaf.org/viaf/144166060362080322153</idno>
              <affiliation ref="#struct-191652"/>
            </author>
            <editor role="depositor">
              <persName>
                <forename>Youri</forename>
                <surname>Timsit</surname>
              </persName>
              <email type="md5">8345a2ed975ba3439a75140c84785620</email>
              <email type="domain">mio.osupytheas.fr</email>
            </editor>
          </titleStmt>
          <editionStmt>
            <edition n="v1" type="current">
              <date type="whenSubmitted">2020-01-21 11:12:00</date>
              <date type="whenModified">2025-04-22 13:48:02</date>
              <date type="whenReleased">2020-01-21 11:26:15</date>
              <date type="whenProduced">2013</date>
              <date type="whenEndEmbargoed">2020-01-21</date>
              <ref type="file" target="https://hal.science/hal-01816598v1/document">
                <date notBefore="2020-01-21"/>
              </ref>
              <ref type="file" subtype="greenPublisher" n="1" target="https://hal.science/hal-01816598v1/file/ijms-14-08252.pdf" id="file-2446856-2331399">
                <date notBefore="2020-01-21"/>
              </ref>
              <ref type="externalLink" target="http://www.mdpi.com/1422-0067/14/4/8252/pdf"/>
            </edition>
            <respStmt>
              <resp>contributor</resp>
              <name key="637319">
                <persName>
                  <forename>Youri</forename>
                  <surname>Timsit</surname>
                </persName>
                <email type="md5">8345a2ed975ba3439a75140c84785620</email>
                <email type="domain">mio.osupytheas.fr</email>
              </name>
            </respStmt>
          </editionStmt>
          <publicationStmt>
            <distributor>CCSD</distributor>
            <idno type="halId">hal-01816598</idno>
            <idno type="halUri">https://hal.science/hal-01816598</idno>
            <idno type="halBibtex">timsit:hal-01816598</idno>
            <idno type="halRefHtml">&lt;i&gt;International Journal of Molecular Sciences&lt;/i&gt;, 2013, 14 (4), pp.8252-8270. &lt;a target="_blank" href="https://dx.doi.org/10.3390/ijms14048252"&gt;&amp;#x27E8;10.3390/ijms14048252&amp;#x27E9;&lt;/a&gt;</idno>
            <idno type="halRef">International Journal of Molecular Sciences, 2013, 14 (4), pp.8252-8270. &amp;#x27E8;10.3390/ijms14048252&amp;#x27E9;</idno>
            <availability status="restricted">
              <licence target="https://creativecommons.org/licenses/by-nc-sa/4.0/">CC BY-NC-SA 4.0 - Attribution - Non-commercial use - ShareAlike<ref corresp="#file-2446856-2331399"/></licence>
            </availability>
          </publicationStmt>
          <seriesStmt>
            <idno type="stamp" n="IRD">IRD - Institut de recherche pour le développement</idno>
            <idno type="stamp" n="INSU">INSU - Institut National des Sciences de l'Univers</idno>
            <idno type="stamp" n="UNIV-TLN">Université de Toulon</idno>
            <idno type="stamp" n="CNRS">CNRS - Centre national de la recherche scientifique</idno>
            <idno type="stamp" n="UNIV-AMU">Aix Marseille Université</idno>
            <idno type="stamp" n="MIO" corresp="OSU-INSTITUT-PYTHEAS">Institut Méditerranéen d'Oceanologie - Mediterranean Institute of Oceanography (MIO)</idno>
            <idno type="stamp" n="OSU-INSTITUT-PYTHEAS">OSU INSTITUT PYTHEAS</idno>
            <idno type="stamp" n="MIO-MEB" corresp="MIO">Microbiologie Environnementale Biotechnologie (MEB)</idno>
            <idno type="stamp" n="MIO-BIOGEO" corresp="MIO">Biogéochimie</idno>
          </seriesStmt>
          <notesStmt>
            <note type="audience" n="2">International</note>
            <note type="popular" n="0">No</note>
            <note type="peer" n="1">Yes</note>
          </notesStmt>
          <sourceDesc>
            <biblStruct>
              <analytic>
                <title xml:lang="en">DNA Self-Assembly: From Chirality to Evolution</title>
                <author role="aut">
                  <persName>
                    <forename type="first">Y.</forename>
                    <surname>Timsit</surname>
                  </persName>
                  <email type="md5">8345a2ed975ba3439a75140c84785620</email>
                  <email type="domain">mio.osupytheas.fr</email>
                  <idno type="idhal" notation="string">youri-timsit</idno>
                  <idno type="idhal" notation="numeric">20065</idno>
                  <idno type="halauthorid" notation="string">3482-20065</idno>
                  <idno type="ORCID">https://orcid.org/0000-0003-0601-7201</idno>
                  <idno type="IDREF">https://www.idref.fr/263483835</idno>
                  <idno type="VIAF">https://viaf.org/viaf/144166060362080322153</idno>
                  <affiliation ref="#struct-191652"/>
                </author>
              </analytic>
              <monogr>
                <idno type="halJournalId" status="VALID">877092</idno>
                <idno type="issn">1661-6596</idno>
                <idno type="eissn">1422-0067</idno>
                <title level="j">International Journal of Molecular Sciences</title>
                <imprint>
                  <publisher>MDPI</publisher>
                  <biblScope unit="volume">14</biblScope>
                  <biblScope unit="issue">4</biblScope>
                  <biblScope unit="pp">8252-8270</biblScope>
                  <date type="datePub">2013</date>
                </imprint>
              </monogr>
              <idno type="doi">10.3390/ijms14048252</idno>
            </biblStruct>
          </sourceDesc>
          <profileDesc>
            <langUsage>
              <language ident="en">English</language>
            </langUsage>
            <textClass>
              <keywords scheme="author">
                <term xml:lang="en">DNA packaging</term>
                <term xml:lang="en">crossover</term>
                <term xml:lang="en">topoisomerase</term>
                <term xml:lang="en">higher-order structures</term>
                <term xml:lang="en">topology</term>
                <term xml:lang="en">chromatin</term>
              </keywords>
              <classCode scheme="halDomain" n="sdv.bbm.bs">Life Sciences [q-bio]/Biochemistry, Molecular Biology/Structural Biology [q-bio.BM]</classCode>
              <classCode scheme="halTypology" n="ART">Journal articles</classCode>
              <classCode scheme="halOldTypology" n="ART">Journal articles</classCode>
              <classCode scheme="halTreeTypology" n="ART">Journal articles</classCode>
            </textClass>
            <abstract xml:lang="en">
              <p>Transient or long-term DNA self-assembly participates in essential genetic functions. The present review focuses on tight DNA-DNA interactions that have recently been found to play important roles in both controlling DNA higher-order structures and their topology. Due to their chirality, double helices are tightly packed into stable right-handed crossovers. Simple packing rules that are imposed by DNA geometry and sequence dictate the overall architecture of higher order DNA structures. Close DNA-DNA interactions also provide the missing link between local interactions and DNA topology, thus explaining how type II DNA topoisomerases may sense locally the global topology. Finally this paper proposes that through its influence on DNA self-assembled structures, DNA chirality played a critical role during the early steps of evolution.</p>
            </abstract>
          </profileDesc>
        </biblFull>
      </listBibl>
    </body>
    <back>
      <listOrg type="structures">
        <org type="laboratory" xml:id="struct-191652" status="VALID">
          <idno type="IdRef">167663925</idno>
          <idno type="ISNI">0000000417586271</idno>
          <idno type="RNSR">201220349W</idno>
          <idno type="ROR">https://ror.org/05258q350</idno>
          <idno type="Wikidata">Q3152368</idno>
          <orgName>Institut méditerranéen d'océanologie</orgName>
          <orgName type="acronym">MIO</orgName>
          <date type="start">2012-01-01</date>
          <desc>
            <address>
              <addrLine>M.I.O. Institut Méditerranéen d'Océanologie Bâtiment Méditerranée163 Avenue de Luminy13288 Marseille</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.mio.univ-amu.fr/</ref>
          </desc>
          <listRelation>
            <relation name="UMR_D235" active="#struct-67872" type="direct"/>
            <relation name="UM110" active="#struct-198056" type="direct"/>
            <relation name="UMR7294" active="#struct-300045" type="direct"/>
            <relation name="UMR7294" active="#struct-303091" type="direct"/>
            <relation name="UMR7294" active="#struct-441569" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-67872" status="VALID">
          <idno type="IdRef">050165224</idno>
          <idno type="ROR">https://ror.org/05q3vnk25</idno>
          <orgName>Institut de Recherche pour le Développement</orgName>
          <orgName type="acronym">IRD</orgName>
          <desc>
            <address>
              <addrLine>SiègeLe Sextant 44, bd de DunkerqueCS 9000913572 Marseille cedex 02</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.ird.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-198056" status="VALID">
          <idno type="IdRef">15863621X</idno>
          <idno type="ISNI">0000 0001 2176 4817</idno>
          <idno type="ROR">https://ror.org/035xkbk20</idno>
          <orgName>Aix Marseille Université</orgName>
          <orgName type="acronym">AMU</orgName>
          <date type="start">2012-01-01</date>
          <desc>
            <address>
              <addrLine>Aix-Marseille UniversitéJardins du Pharo58 Boulevard Charles Livon13284 Marseille cedex 7</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.univ-amu.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-300045" status="VALID">
          <idno type="IdRef">029349265</idno>
          <idno type="ISNI">0000 0001 2154 1736</idno>
          <idno type="ROR">https://ror.org/04kdfz702</idno>
          <idno type="Wikidata">Q3152437</idno>
          <orgName>Institut national des sciences de l'Univers</orgName>
          <orgName type="acronym">INSU - CNRS</orgName>
          <date type="start">2007-04-19</date>
          <desc>
            <address>
              <addrLine>INSU-CNRS3 rue Michel-Ange, 75794 Paris Cedex 16</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.insu.cnrs.fr</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-303091" status="VALID">
          <idno type="IdRef">031122337</idno>
          <idno type="ROR">https://ror.org/02m9kbe37</idno>
          <orgName>Université de Toulon</orgName>
          <orgName type="acronym">UTLN</orgName>
          <desc>
            <address>
              <addrLine>Avenue de l'Université - BP 20132 - 83957 La Garde Cedex</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.univ-tln.fr/</ref>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-441569" status="VALID">
          <idno type="IdRef">02636817X</idno>
          <idno type="ISNI">0000000122597504</idno>
          <idno type="ROR">https://ror.org/02feahw73</idno>
          <orgName>Centre National de la Recherche Scientifique</orgName>
          <orgName type="acronym">CNRS</orgName>
          <date type="start">1939-10-19</date>
          <desc>
            <address>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.cnrs.fr/</ref>
          </desc>
        </org>
      </listOrg>
    </back>
  </text>
</TEI>