Degradation of paraoxon (VX chemical agent simulant) and bacteria by magnesium oxide depends on the crystalline structure of magnesium oxide
Résumé
In this work, our goal was to study the capability of a single metallic oxide to neutralize a chemical agent and to exhibit an antibacterial effect. We tested two types of magnesium oxides, MgO. The first MgO sample tested, which commercial data size characteristic was −325 mesh (MgO-1) destroyed in 3 h, 89.7% of paraoxon and 93.2% of 4-nitrophenol, the first degradation product. The second MgO sample, which commercial data size was <50 nm (MgO-2) neutralized in the same time, 19.5% of paraoxon and 10.9% of 4-nitrophenol. For MgO-1 no degradation products could be detected by GC-MS. MgO-1 had a bactericidal activity on Escherichia coli (6 log in 1 h), and showed a decrease of almost 3 log on a Staphylococcus aureus population in 3 h. MgO-2 caused a decrease of 2 log of a E.coli culture but had no activity against S. aureus. Neither of these two products had an activity on Bacillus subtilis spores. Analytical investigations showed that the real sizes of MgO nanoparticles were 11 nm for MgO-1 and 25 nm for MgO-2. Moreover, their crystalline structures were different. These results highlighted the importance of the size of the nanoparticles and their microscopic arrangements to detoxify chemical products and to inhibit or kill microbial strains. © 2016 Elsevier Ireland Ltd
Mots clés
metal nanoparticle
4-nitrophenol
methylphosphonothioic acid s (2 diisopropylaminoethyl) o ethyl ester
development and aging
growth
chemistry
drug effects
bacterial spore
Gas Chromatography-Mass Spectrometry
Magnesium Oxide
physiology
nitrophenol
phosphorothioic acid derivative
antibacterial activity
Article
Bacillus subtilis
bactericidal activity
controlled study
crystal structure
degradation
detoxification
disinfection
Escherichia coli
mass fragmentography
nonhuman
Staphylococcus aureus
nanoparticle
4 nitrophenol
Metal Nanoparticles
Nitrophenols
Organothiophosphorus Compounds
Paraoxon
Particle Size
Spores
Bacterial