Negative serology of Fasciola hepatica infection in patients with liver cancer in Peru: a preliminary report
Résumé
Introduction: The etiology of several hepatocellular carcinoma (HCC) cases remains largely unknown. Although Fasciola hepatica has been associated with liver fibrosis in Latin America, it has not yet been associated with HCC. This study aimed to determine the existence of specific IgG antibodies against F. hepatica in the serum samples of HCC patients. Methods: In total, 13 serum samples from 13 HCC patients were screened using Fas2-ELISA. Results: Fas2-ELISA demonstrated negative results in all HCC patients included in this study. Conclusions: The pre-existence of F. hepatica infection in HCC patients needs to be further investigated in epidemiological and experimental studies.
Mots clés
Adult
Aged
Aged 80 and over
Animals
Antibodies
Helminth / blood
Carcinoma Hepatocellular / blood
Carcinoma
Hepatocellular / parasitology
Enzyme-Linked Immunosorbent Assay
Fasciola hepatica / immunology
Fascioliasis / complications
Fascioliasis / diagnosis
Female
Humans
Immunoglobulin G / blood
Liver Neoplasms / blood
Liver Neoplasms / parasitology
Male
Middle Aged
Peru
Risk Factors
Young Adult
Origine : Fichiers éditeurs autorisés sur une archive ouverte
Loading...