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Article Dans Une Revue ACS Chemical Neuroscience Année : 2015

Serotonin: a new hope in Alzheimer's disease?

Résumé

Alzheimer's disease (AD) is the most common form of dementia affecting 35 million individuals worldwide. Current AD treatments provide only brief symptomatic relief. It is therefore urgent to replace this symptomatic approach with a curative one. Increasing serotonin signaling as well as developing molecules that enhance serotonin concentration in the synaptic cleft have been debated as possible therapeutic strategies to slow the progression of AD. In this Viewpoint, we discuss exciting new insights regarding the modulation of serotonin signaling for AD prevention and therapy.

Domaines

Neurobiologie
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Dates et versions

hal-01792388 , version 1 (19-02-2020)

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Sylvie Claeysen, Joël Bockaert, Patrizia Giannoni. Serotonin: a new hope in Alzheimer's disease?. ACS Chemical Neuroscience, 2015, 6 (7), pp.940-943. ⟨10.1021/acschemneuro.5b00135⟩. ⟨hal-01792388⟩
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