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Article Dans Une Revue BMC Nephrology Année : 2018

Factors associated with Health-Related Quality of Life in Kidney Transplant Recipients in France

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Background: Health-Related Quality of Life (HRQoL) assessment after kidney transplantation has become an important tool in evaluating outcomes. This study aims to identify the associated factors with HRQoL among a representative sample size of Kidney Transplant Recipients (KTR) at the time of their inclusion in the study. Methods: Data of this cross-sectional design is retrieved from a longitudinal study conducted in five French kidney transplant centers in 2011, and included KTR aged 18 years with a functioning graft for at least 1 year. Measures include demographic, psycho-social and clinical characteristics. To evaluate HRQoL, the Short Form-36 Health Survey (SF-36) and a HRQoL instrument for KTR (ReTransQol) were administered. Multivariate linear regression models were performed. Results: A total of 1424 patients were included, with 61.4% males, and a mean age of 55.7 years (+/- 13.1). Demographic and clinical characteristics were associated with low HRQoL scores for both questionnaires. New variables were found in our study: perceived poor social support and being treated by antidepressants were associated with low scores of Quality of Life (QoL), while internet access was associated with high QoL scores. Conclusion: The originality of our study's findings was that psycho-social variables, particularly KTR treated by antidepressants and having felt unmet needs for any social support, have a negative effect on their QoL. It may be useful to organize a psychological support specifically adapted for patients after kidney transplantation.
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hal-01791586 , version 1 (22-08-2018)

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Yosra Mouelhi, Elisabeth Jouve, Marine Alessandrini, Nathalie Pedinielli, Valerie Moal, et al.. Factors associated with Health-Related Quality of Life in Kidney Transplant Recipients in France. BMC Nephrology, 2018, 19 (1), pp.99. ⟨10.1186/s12882-018-0893-6⟩. ⟨hal-01791586⟩
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