Environmental exposure to agricultural pesticides (EEAP) resulting from the drift of agricultural pesticides applied on fields and is suspected to be a risk factor for several diseases. Geographic Information Systems (GIS) are increasingly used in environmental epidemiological studies to assess EEAP. Crop acreage proximate to subjects residences has been suggested as a surrogate for EEAP. Retrospective characterization of EEAP is essential due to long latency. Earlier data are lacking and limitting the capacity to capture the life-course effects of exposure. We aimed to develop an innovative software to analyze the historical monochromatic aerial images to reconstruct land use to characterize EEAP retrospectively.