Numerical modeling of cartilage growth under mechanical stresses. Mechanical and biological analysis on in vitro «micropellet» model
Résumé
The project concerns the modeling of the growth of new-cartilage samples generated from mesenchymal stem cells. These samples reproduce the embryonic formation of cartilage. We first propose to set up a device for analysing the mechanical features of neocartilage samples and then to investigate the role of mechanical stresses on the extra-cellular matrix production. This approach aims at evaluating and classifying the influence of mechanical stresses in respect of the growth factors on growth process.
Domaines
Biomécanique [physics.med-ph]Origine | Fichiers produits par l'(les) auteur(s) |
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