The Multisensor Time-Frequency Signal Processing (MTFSP) Matlab package is an analysis tool for multichannel non-stationary signals collected from an array of sensors. By combining array signal processing for non-stationary signals and multichannel high resolution time-frequency methods, MTFSP enables applications such as cross-channel causality relationships, automated component separation and direction of arrival estimation, using multisensor time-frequency distributions (MTFDs). MTFSP can address old and new applications such as: abnormality detection in biomedical signals, source localization in wireless communications or condition monitoring and fault detection in industrial plants. It allows e.g. the reproduction of the results presented in [3].