New synthesis of polyfluoroalkanesulfonylureas

This study describes a new synthesis of F-alkanesulfonyl ureas by reaction of the sodium salt of perfluoroalkane sulfonamide (RF = C4F9, C6F13) with some isocyanates in anhydrous THF. The perfluorinated sulfonylureas are obtained, in one step, from moderate to good yields.

Mots clés

F-alkanesulfonyl ureas Sodium salt of perfluoroalkane sulfonamide Isocyanates

Domaines

Chimie thérapeutique Chimie organique Biochimie [q-bio.BM] Cancer

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https://hal.science/hal-01702758

Soumis le : mercredi 7 février 2018-10:57:36

Dernière modification le : mardi 22 octobre 2024-12:18:03

Dates et versions

hal-01702758 , version 1 (07-02-2018)

Identifiants

HAL Id : hal-01702758 , version 1
DOI : 10.1016/j.jfluchem.2007.05.022

Citer

Zohra Benfodda, L. Delon, F. Guillen, H. Blancou. New synthesis of polyfluoroalkanesulfonylureas. Journal of Fluorine Chemistry, 2007, 128 (11), pp.1353 - 1358. ⟨10.1016/j.jfluchem.2007.05.022⟩. ⟨hal-01702758⟩

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CNRS INSA-ROUEN FNCLCC VALDAURELLE COMUE-NORMANDIE UNIMES BS CHIMIE UNIV-MONTPELLIER UNIROUEN IRCM INSA-GROUPE

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