Usefulness of à la carte antigens for bird fancier’s lung serodiagnosis: total dropping extract and/or dropping’s microflora antigens - Archive ouverte HAL Access content directly
Journal Articles Journal of Medical Microbiology Year : 2017

Usefulness of à la carte antigens for bird fancier’s lung serodiagnosis: total dropping extract and/or dropping’s microflora antigens

Abstract

Bird fancier's lung (BFL) is a pulmonary disease caused by inhalation of avian proteins. The involvement of the microorganisms of droppings has been assumed in the past and this idea still persists today. Our study aimed to compare by immunoprecipitation assay the detection of antibodies against both droppings and microorganisms in the sera of patients (n=15) and asymptomatic exposed controls (n=18). We found that 14/15 BFL patients had negative serological results for isolated microorganisms of the droppings, only one positive against Enterobacter sakasakii. Serological arguments were in accordance with diagnosis in 87 % of cases by testing à la carte antigens from each bird dropping versus 20 % using the standard antigenic panel. Otherwise, the microorganisms antigens issued from dropping flora were negative in 93 % of cases. Consequently, it's preferable to use the total extract from the patient's bird droppings to establish the serodiagnosis of the disease.

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Health

Dates and versions

hal-01667609 , version 1 (19-12-2017)

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Adeline Rouzet, Gabriel Reboux, Jean-Charles Dalphin, Paul de Vuyst, Audrey Laboissière, et al.. Usefulness of à la carte antigens for bird fancier’s lung serodiagnosis: total dropping extract and/or dropping’s microflora antigens. Journal of Medical Microbiology, 2017, 66 (10), pp.1467 - 1470. ⟨10.1099/jmm.0.000586⟩. ⟨hal-01667609⟩
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