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Journal Articles Calcium binding proteins Year : 2006

Calcium-Dependent Regulation of Ion Channels.

Abstract

Calcium plays an important role in regulating hundreds of biological processes due to its primary role as one of the most ubiquitous second messengers. As a result, the levels of calcium are tightly regulated as are the peak and trough calcium concentrations during a calcium signal. Calcium levels are controlled via a variety of feedback mechanisms and exchangers/transporters. Here the role of calcium in the feedback regulation of ion channel function is reviewed, with an emphasis on the molecular mechanisms governing calcium-dependent function. In particular, the role of calcium in the regulation of voltage-gated sodium, calcium, and potassium channels are reviewed as well as its effects on the ryanodine receptor.
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Dates and versions

hal-01652606 , version 1 (30-11-2017)

Identifiers

  • HAL Id : hal-01652606 , version 1
  • PUBMED : 28757812

Cite

Vikas N Shah, Benjamin Chagot, Walter J Chazin. Calcium-Dependent Regulation of Ion Channels.. Calcium binding proteins, 2006, pp.203-212. ⟨hal-01652606⟩
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