This study investigated time patterns and the relationships between perceived stress, recovery, control, attention lapses, and defense mechanisms (DM) during a 12-month wintering in Concordia polar station with an international crew of 14 volunteers. This ICE (Isolated, Confined, Extreme) environment induced some stress, mainly in the social dimension and showed relationships (a) between DM and both stress and recovery and (b) between recovery and perceived control, highlighting the roles of DM and control in psychological adaptation. These results offer additional insights into the affective, social, and cognitive processes involved in adaptation. The findings suggest that preventive psychological countermeasures should be developed for crew members to counteract detrimental psychological outcomes and to improve adaptation to long-duration ICE situations such as planned human interplanetary space missions.