In silico prediction of RNA secondary structure - Archive ouverte HAL Access content directly
Book Sections Year : 2017

In silico prediction of RNA secondary structure


The secondary structure of an RNA molecule represents the base-pairing interactions within the molecule and fundamentally determines its overall structure. In this chapter, we overview the main approaches and existing tools for predicting RNA secondary structures, as well as methods for identifying noncoding RNAs from genomic sequences or RNA sequencing data. We then focus on the identification of a well-known class of small noncoding RNAs, namely microRNAs, which play very important roles in many biological processes through regulating post-transcriptionally the expression of genes and which dysregulation has been shown to be involved in several human diseases.
No file

Dates and versions

hal-01630646 , version 1 (07-11-2017)



Fariza Tahi, van Du Tran, Anouar Boucheham. In silico prediction of RNA secondary structure. Methods in Molecular Biology, 1543, pp.145--168, 2017, ⟨10.1007/978-1-4939-6716-2_7⟩. ⟨hal-01630646⟩
168 View
0 Download



Gmail Mastodon Facebook X LinkedIn More