Synthesis of a New Linear-Cyclic Ditopic Polyazaligand with a Xylenyl Linker - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Synthetic Communications Année : 2009

Synthesis of a New Linear-Cyclic Ditopic Polyazaligand with a Xylenyl Linker

Résumé

The synthesis of a new linear-cyclic ditopic polyazaligand with a xylenyl linker 1 is described. The sequence is based on the stoichiometric reaction of a dissymmetrical biselectrophilic reagent, p-(chloromethyl)benzyl-p-toluenesulfonate, with phosphorylcyclam to give rise to an original intermediate possessing a p-chloroxylenyl pendant arm. The subsequent reaction of this compound with glyoxal-protected linear tetraamine, followed by deprotection steps, leads to the desired ditopic ligand with a good overall yield
Fichier non déposé

Dates et versions

hal-01629515 , version 1 (06-11-2017)

Identifiants

Citer

Nathalie Le Bris, Hélène Bernard, Zein El Abidine Chamas, Henri Handel. Synthesis of a New Linear-Cyclic Ditopic Polyazaligand with a Xylenyl Linker. Synthetic Communications, 2009, 39 (11), pp.1992 - 2000. ⟨10.1080/00397910802630203⟩. ⟨hal-01629515⟩
51 Consultations
0 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More