Convergent evolution of the adaptive immune response in jawed vertebrates and cyclostomes: An evolutionary biology approach based study - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Developmental and Comparative Immunology Année : 2017

Convergent evolution of the adaptive immune response in jawed vertebrates and cyclostomes: An evolutionary biology approach based study

Résumé

Two different adaptive immune systems (AIS) are present in the two phyla of vertebrates (jawed vertebrates and cyclostomes). The jawed vertebrate system is based on IG/TCR/RAG/MHC while the cyclostome system is based on VLRC5 and AID-like enzymes both systems using homologous Cell types (B-cell and B-cell Like, T-cell and T-cell like). We will present our current view of the evolution of these two AISs and present alternative hypotheses that could explain the apparent convergent evolution of the two systems. We will also discuss why comparative immunology analyses should be based on evolutionary biology approaches and not on the scale of progress one.
Fichier non déposé

Dates et versions

hal-01622250 , version 1 (24-10-2017)

Identifiants

Citer

Jose Ricardo Morales Poole, Julien Paganini, Pierre Pontarotti. Convergent evolution of the adaptive immune response in jawed vertebrates and cyclostomes: An evolutionary biology approach based study. Developmental and Comparative Immunology, 2017, 75, pp.120 - 126. ⟨10.1016/j.dci.2017.02.011⟩. ⟨hal-01622250⟩
87 Consultations
0 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More