Numerical eligibility criteria in clinical protocols: Annotation, automatic detection and interpretation - Archive ouverte HAL
Communication Dans Un Congrès Année : 2017

Numerical eligibility criteria in clinical protocols: Annotation, automatic detection and interpretation

Résumé

Clinical trials are fundamental for evaluating therapies and diagnosis techniques. Yet, recruitment of patients remains a real challenge. Eligibility criteria are related to terms but also to patient laboratory results usually expressed with numerical values. Both types of information are important for patient selection. We propose to address the processing of numerical values. A set of sentences extracted from clinical trials are manually annotated by four annotators. Four categories are distinguished: C (concept), V (numerical value), U (unit), O (out position). According to the pairs of annotators, the interannotator agreement on the whole annotation sequence CV U goes up to 0.78 and 0.83. Then, an automatic method using CFRs is exploited for creating a supervised model for the recognition of these categories. The obtained F-measure is 0.60 for C, 0.82forV, and 0.76 for U. © Springer International Publishing AG 2017.

Dates et versions

hal-01618930 , version 1 (18-10-2017)
hal-01618930 , version 2 (21-11-2017)

Identifiants

Citer

Vincent Claveau, L.E.S. Oliveira, G. Bouzillé, M. Cuggia, C.M.C. Moro, et al.. Numerical eligibility criteria in clinical protocols: Annotation, automatic detection and interpretation. 16th Conference on Artificial Intelligence in Medicine, AIME 2017, Jun 2017, Vienna, Austria. ⟨10.1007/978-3-319-59758-4_22⟩. ⟨hal-01618930v1⟩

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