Tomatoes and lycopene : inflammatory modulator effects
Résumé
Tomato, tomato products as well as lycopene consumption are overall acknowledged to
exert anti-inflammatory effects. This has been reported in numerous in vitro, animal and clinical
studies, on various tissue and cell types, including adipose tissue and adipocytes, and in several
physiopathological contexts, such as cardiovascular diseases, type-2 diabetes, obesity or metabolic
syndrome. These anti-inflammatory effects are partly related to tomato and lycopene impact on
inflammatory signaling pathways.
The goal of this review is to summarize the current knowledge on this topic and to identify gaps that
remain to be filled and data that still need to be reinforced in order to definitely demonstrate the
interest of tomato or lycopene consumption to blunt the inflammation associated with
cardiometabolic diseases.
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