Using murine colitis models to analyze probiotics–host interactions - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue (Article De Synthèse) FEMS Microbiology Reviews Année : 2017

Using murine colitis models to analyze probiotics–host interactions

Résumé

Probiotics are defined as ‘live microorganisms which when administered in adequate amounts confer a health benefit on the host’. So, to consider a microorganism as a probiotic, a demonstrable beneficial effect on the health host should be shown as well as an adequate defined safety status and the capacity to survive transit through the gastrointestinal tract and to storage conditions. In this review, we present an overview of the murine colitis models currently employed to test the beneficial effect of the probiotic strains as well as an overview of the probiotics already tested. Our aim is to highlight both the importance of the adequate selection of the animal model to test the potential probiotic strains and of the value of the knowledge generated by these in vivo tests.

Dates et versions

hal-01602302 , version 1 (02-10-2017)

Licence

Copyright (Tous droits réservés)

Identifiants

Citer

Rebeca Martin Rosique, Florian Chain, Sylvie Miquel, Jean-Paul Motta, Nathalie Vergnolle, et al.. Using murine colitis models to analyze probiotics–host interactions. FEMS Microbiology Reviews, 2017, 41 (Supp_1), pp.S49-S70. ⟨10.1093/femsre/fux035⟩. ⟨hal-01602302⟩
232 Consultations
0 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More