<?xml version="1.0" encoding="utf-8"?>
<TEI xmlns="http://www.tei-c.org/ns/1.0" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:hal="http://hal.archives-ouvertes.fr/" xmlns:gml="http://www.opengis.net/gml/3.3/" xmlns:gmlce="http://www.opengis.net/gml/3.3/ce" version="1.1" xsi:schemaLocation="http://www.tei-c.org/ns/1.0 http://api.archives-ouvertes.fr/documents/aofr-sword.xsd">
  <teiHeader>
    <fileDesc>
      <titleStmt>
        <title>HAL TEI export of hal-01601640</title>
      </titleStmt>
      <publicationStmt>
        <distributor>CCSD</distributor>
        <availability status="restricted">
          <licence target="https://creativecommons.org/publicdomain/zero/1.0/">CC0 1.0 - Universal</licence>
        </availability>
        <date when="2026-05-13T23:59:41+02:00"/>
      </publicationStmt>
      <sourceDesc>
        <p part="N">HAL API Platform</p>
      </sourceDesc>
    </fileDesc>
  </teiHeader>
  <text>
    <body>
      <listBibl>
        <biblFull>
          <titleStmt>
            <title xml:lang="en">Differential quantitative proteome analysis of Escherichia coli grown on acetate versus glucose</title>
            <author role="aut">
              <persName>
                <forename type="first">Christian</forename>
                <surname>Treitz</surname>
              </persName>
              <idno type="halauthorid">1234407-0</idno>
              <affiliation ref="#struct-511554"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Brice</forename>
                <surname>Enjalbert</surname>
              </persName>
              <email type="md5">5ca4cc0d5049e8e0ecd06a0cd9536a09</email>
              <email type="domain">insa-toulouse.fr</email>
              <idno type="idhal" notation="string">brice-enjalbert</idno>
              <idno type="idhal" notation="numeric">21796</idno>
              <idno type="halauthorid" notation="string">35025-21796</idno>
              <idno type="ORCID">https://orcid.org/0000-0003-1291-1373</idno>
              <idno type="IDREF">https://www.idref.fr/072465581</idno>
              <affiliation ref="#struct-135535"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Jean-Charles</forename>
                <surname>Portais</surname>
              </persName>
              <email type="md5">8ee130aca7a8eb07f528f71680788f01</email>
              <email type="domain">insa-toulouse.fr</email>
              <idno type="idhal" notation="numeric">1097795</idno>
              <idno type="halauthorid" notation="string">875975-1097795</idno>
              <idno type="ORCID">https://orcid.org/0000-0002-3480-0933</idno>
              <idno type="IDREF">https://www.idref.fr/058637397</idno>
              <affiliation ref="#struct-135535"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Fabien</forename>
                <surname>Letisse</surname>
              </persName>
              <email type="md5">19f2c108c10bc2b1d51016b230f10aea</email>
              <email type="domain">insa-toulouse.fr</email>
              <idno type="idhal" notation="string">fabien-letisse</idno>
              <idno type="idhal" notation="numeric">176275</idno>
              <idno type="halauthorid" notation="string">993292-176275</idno>
              <idno type="ORCID">https://orcid.org/0000-0002-1490-0152</idno>
              <idno type="IDREF">https://www.idref.fr/082845913</idno>
              <affiliation ref="#struct-135535"/>
            </author>
            <author role="crp">
              <persName>
                <forename type="first">Andreas</forename>
                <surname>Tholey</surname>
              </persName>
              <email type="md5">ab10f65bac6858e45dc26ad4f1ff59db</email>
              <email type="domain">iem.uni-kiel.de</email>
              <idno type="idhal" notation="numeric">1018654</idno>
              <idno type="halauthorid" notation="string">879899-1018654</idno>
              <affiliation ref="#struct-511554"/>
            </author>
            <editor role="depositor">
              <persName>
                <forename>Archive Ouverte</forename>
                <surname>ProdInra</surname>
              </persName>
              <email type="md5">9e5ed7d56b52b3d4383123b1ffb42236</email>
              <email type="domain">inrae.fr</email>
            </editor>
          </titleStmt>
          <editionStmt>
            <edition n="v1" type="current">
              <date type="whenSubmitted">2019-06-05 16:35:57</date>
              <date type="whenModified">2025-09-23 14:22:13</date>
              <date type="whenReleased">2019-06-05 17:20:37</date>
              <date type="whenProduced">2016</date>
              <date type="whenEndEmbargoed">2019-06-05</date>
              <ref type="file" target="https://hal.science/hal-01601640v1/document">
                <date notBefore="2019-06-05"/>
              </ref>
              <ref type="file" subtype="publisherAgreement" n="1" target="https://hal.science/hal-01601640v1/file/Treitz%20Tholey%202016%20sans%20note.pdf" id="file-2138188-2140095">
                <date notBefore="2019-06-05"/>
              </ref>
              <ref type="externalLink" target="https://hal.archives-ouvertes.fr/hal-01601640/file/Treitz%20Tholey%202016%20sans%20note.pdf"/>
              <fs>
                <f name="inra_etatDocument_local" notation="string" n="VE">
                  <string>inra_etatDocument_local_VE</string>
                </f>
                <f name="inra_publicVise_local" notation="string" n="SC">
                  <string>inra_publicVise_local_SC</string>
                </f>
              </fs>
            </edition>
            <respStmt>
              <resp>contributor</resp>
              <name key="132775">
                <persName>
                  <forename>Archive Ouverte</forename>
                  <surname>ProdInra</surname>
                </persName>
                <email type="md5">9e5ed7d56b52b3d4383123b1ffb42236</email>
                <email type="domain">inrae.fr</email>
              </name>
            </respStmt>
          </editionStmt>
          <publicationStmt>
            <distributor>CCSD</distributor>
            <idno type="halId">hal-01601640</idno>
            <idno type="halUri">https://hal.science/hal-01601640</idno>
            <idno type="halBibtex">treitz:hal-01601640</idno>
            <idno type="halRefHtml">&lt;i&gt;Proteomics&lt;/i&gt;, 2016, 16 (21), pp.2742-2746. &lt;a target="_blank" href="https://dx.doi.org/10.1002/pmic.201600303"&gt;&amp;#x27E8;10.1002/pmic.201600303&amp;#x27E9;&lt;/a&gt;</idno>
            <idno type="halRef">Proteomics, 2016, 16 (21), pp.2742-2746. &amp;#x27E8;10.1002/pmic.201600303&amp;#x27E9;</idno>
            <availability status="restricted">
              <licence target="https://hal.science/licences/copyright/">Copyright - All rights reserved<ref corresp="#file-2138188-2140095"/></licence>
            </availability>
          </publicationStmt>
          <seriesStmt>
            <idno type="stamp" n="CNRS">CNRS - Centre national de la recherche scientifique</idno>
            <idno type="stamp" n="INSA-TOULOUSE">Institut National des Sciences Appliquées de Toulouse</idno>
            <idno type="stamp" n="INRA">INRA - Institut national de la recherche agronomique</idno>
            <idno type="stamp" n="AGREENIUM">Archive ouverte en agrobiosciences</idno>
            <idno type="stamp" n="INSA-GROUPE">Groupe INSA</idno>
            <idno type="stamp" n="TBI" corresp="INSA-TOULOUSE">Toulouse Biotechnology Institute</idno>
            <idno type="stamp" n="INRAE">Institut National de Recherche en Agriculture, Alimentation et Environnement</idno>
            <idno type="stamp" n="INRAEOCCITANIETOULOUSE" corresp="INRAE">INRAE Occitanie Toulouse</idno>
            <idno type="stamp" n="TBI-PRISM" corresp="TBI">Pôle PRISM du laboratoire TBI</idno>
            <idno type="stamp" n="TBI-TECH" corresp="TBI">Pôle Technologique</idno>
          </seriesStmt>
          <notesStmt>
            <note type="audience" n="1">Not set</note>
            <note type="popular" n="0">No</note>
            <note type="peer" n="1">Yes</note>
          </notesStmt>
          <sourceDesc>
            <biblStruct>
              <analytic>
                <title xml:lang="en">Differential quantitative proteome analysis of Escherichia coli grown on acetate versus glucose</title>
                <author role="aut">
                  <persName>
                    <forename type="first">Christian</forename>
                    <surname>Treitz</surname>
                  </persName>
                  <idno type="halauthorid">1234407-0</idno>
                  <affiliation ref="#struct-511554"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Brice</forename>
                    <surname>Enjalbert</surname>
                  </persName>
                  <email type="md5">5ca4cc0d5049e8e0ecd06a0cd9536a09</email>
                  <email type="domain">insa-toulouse.fr</email>
                  <idno type="idhal" notation="string">brice-enjalbert</idno>
                  <idno type="idhal" notation="numeric">21796</idno>
                  <idno type="halauthorid" notation="string">35025-21796</idno>
                  <idno type="ORCID">https://orcid.org/0000-0003-1291-1373</idno>
                  <idno type="IDREF">https://www.idref.fr/072465581</idno>
                  <affiliation ref="#struct-135535"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Jean-Charles</forename>
                    <surname>Portais</surname>
                  </persName>
                  <email type="md5">8ee130aca7a8eb07f528f71680788f01</email>
                  <email type="domain">insa-toulouse.fr</email>
                  <idno type="idhal" notation="numeric">1097795</idno>
                  <idno type="halauthorid" notation="string">875975-1097795</idno>
                  <idno type="ORCID">https://orcid.org/0000-0002-3480-0933</idno>
                  <idno type="IDREF">https://www.idref.fr/058637397</idno>
                  <affiliation ref="#struct-135535"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Fabien</forename>
                    <surname>Letisse</surname>
                  </persName>
                  <email type="md5">19f2c108c10bc2b1d51016b230f10aea</email>
                  <email type="domain">insa-toulouse.fr</email>
                  <idno type="idhal" notation="string">fabien-letisse</idno>
                  <idno type="idhal" notation="numeric">176275</idno>
                  <idno type="halauthorid" notation="string">993292-176275</idno>
                  <idno type="ORCID">https://orcid.org/0000-0002-1490-0152</idno>
                  <idno type="IDREF">https://www.idref.fr/082845913</idno>
                  <affiliation ref="#struct-135535"/>
                </author>
                <author role="crp">
                  <persName>
                    <forename type="first">Andreas</forename>
                    <surname>Tholey</surname>
                  </persName>
                  <email type="md5">ab10f65bac6858e45dc26ad4f1ff59db</email>
                  <email type="domain">iem.uni-kiel.de</email>
                  <idno type="idhal" notation="numeric">1018654</idno>
                  <idno type="halauthorid" notation="string">879899-1018654</idno>
                  <affiliation ref="#struct-511554"/>
                </author>
              </analytic>
              <monogr>
                <idno type="halJournalId" status="VALID">18306</idno>
                <idno type="issn">1615-9853</idno>
                <idno type="eissn">1615-9861</idno>
                <title level="j">Proteomics</title>
                <imprint>
                  <publisher>Wiley-VCH Verlag</publisher>
                  <biblScope unit="volume">16</biblScope>
                  <biblScope unit="issue">21</biblScope>
                  <biblScope unit="pp">2742-2746</biblScope>
                  <date type="datePub">2016</date>
                </imprint>
              </monogr>
              <idno type="doi">10.1002/pmic.201600303</idno>
              <idno type="prodinra">387139</idno>
              <idno type="pubmed">27604403</idno>
              <idno type="wos">000387168600002</idno>
              <ref target="https://archives-publications.inrae.fr/387139.pdf" type="seeAlso"/>
            </biblStruct>
          </sourceDesc>
          <profileDesc>
            <langUsage>
              <language ident="en">English</language>
            </langUsage>
            <textClass>
              <keywords scheme="author">
                <term xml:lang="en">metabolic network</term>
                <term xml:lang="en">systems biology</term>
                <term xml:lang="en">protein</term>
                <term xml:lang="en">biological system</term>
                <term xml:lang="en">2D-LC MS</term>
                <term xml:lang="en">isobaric labeling</term>
                <term xml:lang="fr">escherichia coli</term>
                <term xml:lang="fr">système biologique</term>
                <term xml:lang="fr">protéine</term>
                <term xml:lang="fr">protéome</term>
              </keywords>
              <classCode scheme="halDomain" n="sdv">Life Sciences [q-bio]</classCode>
              <classCode scheme="halDomain" n="sdv.bbm">Life Sciences [q-bio]/Biochemistry, Molecular Biology</classCode>
              <classCode scheme="halDomain" n="sdv.bbm.gtp">Life Sciences [q-bio]/Biochemistry, Molecular Biology/Genomics [q-bio.GN]</classCode>
              <classCode scheme="vocinrae-old" n="protéome">protéome</classCode>
              <classCode scheme="vocinrae-old" n="système biologique">système biologique</classCode>
              <classCode scheme="vocinrae-old" n="protéine">protéine</classCode>
              <classCode scheme="vocinrae-old" n="escherichia coli">escherichia coli</classCode>
              <classCode scheme="halTypology" n="ART">Journal articles</classCode>
              <classCode scheme="halOldTypology" n="ART">Journal articles</classCode>
              <classCode scheme="halTreeTypology" n="ART.DATAPAPER">Journal articles - Data paper</classCode>
            </textClass>
            <abstract xml:lang="en">
              <p>Relative protein abundances of Escherichia coli MG1655 growing exponentially on minimal medium with acetate or glucose as the sole carbon source were investigated in a quantitative shotgun proteome analysis with TMT6-plex isobaric tags. Peptides were separated by high resolution high/low pH 2D-LC, using an optimized fraction pooling scheme followed by mass spectrometric analysis. Quantitative data were acquired for 2099 proteins covering 49% of the predicted E. coli proteins, showing system-wide effects of growth conditions. In total, 507 proteins showed a fold change of at least 1.5 and 205 proteins changed by more than twofold. Significant differences in abundance were observed for most of the proteins in the central carbon metabolism and in proteins relevant for amino acid and protein synthesis, processing of environmental information and scavenging of a variety of alternate carbon sources. Periplasmic-binding proteins were also more abundant on acetate, especially proteins involved in scavenging extracellular resources such as sugars. All MS data have been deposited to the ProteomeXchange Consortium via the PRIDE partner repository (dataset identifier PXD003863).</p>
            </abstract>
          </profileDesc>
        </biblFull>
      </listBibl>
    </body>
    <back>
      <listOrg type="structures">
        <org type="laboratory" xml:id="struct-511554" status="INCOMING">
          <orgName>Systematische Proteomforschung &amp; Bioanalytik, Institut für Experimentelle Medizin</orgName>
          <desc>
            <address>
              <country key="DE"/>
            </address>
          </desc>
          <listRelation>
            <relation active="#struct-462123" type="direct"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-135535" status="OLD">
          <idno type="IdRef">155508717</idno>
          <orgName>Laboratoire d'Ingénierie des Systèmes Biologiques et des Procédés</orgName>
          <orgName type="acronym">LISBP</orgName>
          <date type="start">2007-01-01</date>
          <date type="end">2019-07-05</date>
          <desc>
            <address>
              <addrLine>135 Avenue de rangueil 31077 Toulouse cedex 04</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.lisbp.fr/fr/index.html</ref>
          </desc>
          <listRelation>
            <relation name="UMR0792" active="#struct-92114" type="direct"/>
            <relation active="#struct-116255" type="direct"/>
            <relation active="#struct-301232" type="indirect"/>
            <relation active="#struct-443875" type="indirect"/>
            <relation name="UMR5504" active="#struct-441569" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-462123" status="VALID">
          <idno type="IdRef">027909913</idno>
          <idno type="ISNI">0000000121539986</idno>
          <idno type="ROR">https://ror.org/04v76ef78</idno>
          <orgName>Christian-Albrechts-Universität zu Kiel = Christian-Albrechts University of Kiel = Université Christian-Albrechts de Kiel</orgName>
          <orgName type="acronym">CAU</orgName>
          <desc>
            <address>
              <addrLine>Christian-Albrechts-Platz 4, 24118 Kiel, Germany</addrLine>
              <country key="DE"/>
            </address>
            <ref type="url">http://www.uni-kiel.de/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-92114" status="OLD">
          <idno type="ROR">https://ror.org/01x3gbx83</idno>
          <orgName>Institut National de la Recherche Agronomique</orgName>
          <orgName type="acronym">INRA</orgName>
          <date type="start">1946-05-18</date>
          <date type="end">2019-12-31</date>
          <desc>
            <address>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.inra.fr</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-116255" status="VALID">
          <idno type="IdRef">026388766</idno>
          <idno type="ISNI">0000 0001 2286 8343</idno>
          <idno type="ROR">https://ror.org/01h8pf755</idno>
          <idno type="Wikidata">Q858979</idno>
          <orgName>Institut National des Sciences Appliquées - Toulouse</orgName>
          <orgName type="acronym">INSA Toulouse</orgName>
          <date type="start">1963-10-21</date>
          <desc>
            <address>
              <addrLine>135, avenue de Rangueil - 31077 Toulouse cedex 4</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.insa-toulouse.fr</ref>
          </desc>
          <listRelation>
            <relation active="#struct-301232" type="direct"/>
            <relation active="#struct-443875" type="direct"/>
          </listRelation>
        </org>
        <org type="regroupinstitution" xml:id="struct-301232" status="VALID">
          <idno type="IdRef">162105150</idno>
          <orgName>Institut National des Sciences Appliquées</orgName>
          <orgName type="acronym">INSA</orgName>
          <desc>
            <address>
              <country key="FR"/>
            </address>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-443875" status="VALID">
          <idno type="ROR">https://ror.org/017tgbk05</idno>
          <orgName>Communauté d'universités et établissements de Toulouse</orgName>
          <orgName type="acronym">Comue de Toulouse</orgName>
          <desc>
            <address>
              <addrLine>41 Allée Jules Guesde, 31000 Toulouse</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.univ-toulouse.fr/</ref>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-441569" status="VALID">
          <idno type="IdRef">02636817X</idno>
          <idno type="ISNI">0000000122597504</idno>
          <idno type="ROR">https://ror.org/02feahw73</idno>
          <orgName>Centre National de la Recherche Scientifique</orgName>
          <orgName type="acronym">CNRS</orgName>
          <date type="start">1939-10-19</date>
          <desc>
            <address>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.cnrs.fr/</ref>
          </desc>
        </org>
      </listOrg>
    </back>
  </text>
</TEI>