Biobased 3-hydroxypropionic acid through a new integrated process of glycerol bioconversion and membrane-assisted reactive extraction.
Résumé
Tremendous growth of biodiesel manufacturing industries --> glycerol as a main byproduct. Need for developing biotechnological processes to convert glycerol into high-added value chemicals. 3-Hydroxypropionic acid (3-HP): significant platform chemical from which various specialty chemicals can be synthesized. Currently produced by chemical methods, but biotechnological production not well established Until now, among lactic acid bacteria, only bacteria of the Lactobacillus genus and specially L. reuteri have been shown to produce 3-HP from glycerol, although at low productivity. 3-HP and its metabolic intermediate 3-hydroxypropionaldehyde (3-HPA) are suspected to exhibit inhibitory or toxic effects on the producing microorganisms
--> ISPR (In Situ Product Recovery) = potential strategy to relieve the stress, increase the performance of microbial cells and recover the molecule of interest => Study of the impact of the integrated process on bioconversion productivity and cell physiological state.
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Poster Burgé_Chemarin_French Nordic seminar_2016.pdf (976.43 Ko)
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