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Journal Articles Journal of Synchrotron Radiation Year : 2016

Nuclear incorporation of iron during the eukaryotic cell cycle

Abstract

Scanning X-ray fluorescence microscopy has been used to probe the distribution of S, P and Fe within cell nuclei. Nuclei, which may have originated at different phases of the cell cycle, are found to show very different levels of Fe present with a strongly inhomogeneous distribution. P and S signals, presumably from DNA and associated nucleosomes, are high and relatively uniform across all the nuclei; these agree with X-ray phase contrast projection microscopy images of the same samples. Possible reasons for the Fe incorporation are discussed
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hal-01572923 , version 1 (08-08-2017)

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Ian Robinson, Yang Yang, Fucai Zhang, Christophe Lynch, Mohammed Yusuf, et al.. Nuclear incorporation of iron during the eukaryotic cell cycle. Journal of Synchrotron Radiation, 2016, 23, pp.1490-1497. ⟨10.1107/S1600577516012807⟩. ⟨hal-01572923⟩
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