N1- and N7-substituted sibiriline derivatives and their use as inhibitor of cellular necroptosis. - Archive ouverte HAL Accéder directement au contenu
Brevet Année : 2017

N1- and N7-substituted sibiriline derivatives and their use as inhibitor of cellular necroptosis.

Résumé

The present invention relates to new N1-and N7-substituted sibiriline derivatives of the following general formula (I): (I) or a pharmaceutically acceptable salt and/or solvate thereof, notably for use as drug, in particular for use as inhibitor of cellular necroptosis. The present invention also relates to a pharmaceutical composition comprising such a compound and processes to prepare such a compound. The present invention also encompasses the use of a compound of the general formula (I) for organs preservation.
Fichier non déposé

Dates et versions

hal-01545901 , version 1 (23-06-2017)

Identifiants

  • HAL Id : hal-01545901 , version 1

Citer

Marie-Thérèse Dimanche-Boitrel, Stéphane Bach, Claire Delehouze, Peter Goekjian, Arnaud Comte. N1- and N7-substituted sibiriline derivatives and their use as inhibitor of cellular necroptosis.. France, Patent n° : WO2017064216. CO2GLYCO : Equipe de Chimie Organique 2-Glycochimie. 2017. ⟨hal-01545901⟩
155 Consultations
0 Téléchargements

Partager

Gmail Facebook X LinkedIn More