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            <funder>We acknowledge financial support from CNRS (IR-RMN FR3050, TGIR-RMN00874) and from the European Research Council (ERC) under the European Union's Horizon 2020 research and innovation programme (ERC-2015-CoG GA No. 648974). J.S. is supported by a MC incoming fellowship (REA Grant Agreement No. 661799 "COMPLEX-FAST- MAS"). T.S. and K.C. acknowledge funding from German Federal Ministry of Education and Research (BMBF Grant No. 031A178).</funder>
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            <note type="commentary">We acknowledge Prof Matthias Ernst, ETH, Zurich, for useful discussions and Dr Rajalakshmi and Dr Kaustubh Mote for proofreading the manuscript. </note>
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                <term xml:lang="en"> MAS</term>
                <term xml:lang="en"> NMR</term>
                <term xml:lang="en"> AlkL</term>
                <term xml:lang="en"> beta-barrel membrane protein</term>
                <term xml:lang="en"> GB1</term>
                <term xml:lang="en"> protein</term>
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                <term xml:lang="en">structure determination</term>
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              <p>Very fast magic-angle spinning (MAS &gt; 80 kHz) NMR combined with high-field magnets has enabled the acquisition of proton-detected spectra in fully protonated solid samples with sufficient resolution and sensitivity. One of the primary challenges in structure determination of protein is observing long-range H-1-H-1 contacts. Here we use band-selective spin-lock pulses to obtain selective H-1-H-1 contacts (e.g., H-N-H-N) on the order of 5-6 angstrom in fully protonated proteins at 111 kHz MAS. This approach is a major advancement in structural characterization of proteins given that magnetization can be selectively transferred between protons that are 5-6 angstrom apart despite the presence of other protons at shorter distance. The observed contacts are similar to those previously observed only in perdeuterated proteins with selective protonation. Simulations and experiments show the proposed method has performance that is superior to that of the currently used methods. The method is demonstrated on GB1 and a beta-barrel membrane protein, AlkL.</p>
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