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Article Dans Une Revue Nature Methods Année : 2015

EEG and functional ultrasound imaging in mobile rats

Lim-Anna Sieu
  • Fonction : Auteur
Antoine Bergel
  • Fonction : Auteur
Elodie Tiran
  • Fonction : Auteur
Thomas Deffieux
Mathieu Pernot
Jean-Luc Gennisson
Mickael Tanter

Résumé

We developed an integrated experimental framework that extends the brain exploration capabilities of functional ultrasound imaging to awake and mobile rats. In addition to acquiring hemodynamic data, this method further allows parallel access to electroencephalography (EEG) recordings of neuronal activity. We illustrate this approach with two proofs of concept: a behavioral study on theta rhythm activation in a maze running task and a disease-related study on spontaneous epileptic seizures.

Dates et versions

hal-01541358 , version 1 (19-06-2017)

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Lim-Anna Sieu, Antoine Bergel, Elodie Tiran, Thomas Deffieux, Mathieu Pernot, et al.. EEG and functional ultrasound imaging in mobile rats. Nature Methods, 2015, 12 (9), pp.831+. ⟨10.1038/NMETH.3506⟩. ⟨hal-01541358⟩
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