Efficient conversion of alkenes to chlorohydrins by a Ru-based artificial enzyme. - Archive ouverte HAL Access content directly
Journal Articles Chemical Communications Year : 2017

Efficient conversion of alkenes to chlorohydrins by a Ru-based artificial enzyme.

Abstract

Artificial enzymes are required to catalyse non-natural reactions. Here, a hybrid catalyst was developed by embedding a novel Ru complex in the transport protein NikA. The protein scaffold activates the bound Ru complex to produce a catalyst with high regio- and stereo-selectivity. The hybrid efficiently and stably produced α-hydroxy-β-chloro chlorohydrins from alkenes (up to 180 TON with a TOF of 1050 h−1).
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Dates and versions

hal-01501535 , version 1 (04-04-2017)

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Sarah Lopez, Laurianne Rondot, Christine Cavazza, Marina Iannello, Elisabetta Boeri Erba, et al.. Efficient conversion of alkenes to chlorohydrins by a Ru-based artificial enzyme.. Chemical Communications, 2017, 53 (25), pp.3579-3582. ⟨10.1039/C6CC08873B⟩. ⟨hal-01501535⟩
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