Aerobic metabolism and cardiac activity in the descendants of zebrafish exposed to pyrolytic polycyclic aromatic hydrocarbons - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Environmental Science and Pollution Research Année : 2014

Aerobic metabolism and cardiac activity in the descendants of zebrafish exposed to pyrolytic polycyclic aromatic hydrocarbons

Résumé

The increase of anthropogenic activities on coastal areas induces discharges of Polycyclic Aromatic 16 Hydrocarbons (PAHs) in aquatic ecosystem. PAHs effects depend on their concentration and the way of 17 contamination, but also on the different developmental stages of the organism. Zebrafish were exposed to 18 relevant concentration of pyrolytic PAHs from the first meal (i.e. 5 day post fertilization, dpf) to mature adults. 19 Parental effect of this type of exposure was evaluated through the assessment of aerobic metabolic scope, cardiac 20 frequency and cardiac mRNA expression on larval and/or embryo progeny of contaminated fish. Our results 21 suggest that cardiac frequency increased in larval descendants of fish exposed to the environmental 22 concentration of pyrolytic PAHs (i.e. 5ng.g-1 of food), while a lack of effect on aerobic metabolism in 5 dpf 23 larvae was highlighted. A surexpression of mRNA related to the cardiac calcium transporting ATPase atp2a2a, a 24 protein essential for contraction, is in accordance with this increasing cardiac frequency. Even if cardiac 25 development genes cmlc1 and tnnt2a were not affected at early lifestages tested, complementary work on cardiac 26 structure could be interesting to better understand PAHs action. 27 28
Fichier principal
Vignette du fichier
Lucas et al. 2014.pdf (606.41 Ko) Télécharger le fichier
Origine Fichiers produits par l'(les) auteur(s)
Loading...

Dates et versions

hal-01451554 , version 1 (01-02-2017)

Identifiants

Citer

Julie Lucas, Prescilla Perrichon, Marine Nouhaud, Alexandre Audras, Isabelle Leguen, et al.. Aerobic metabolism and cardiac activity in the descendants of zebrafish exposed to pyrolytic polycyclic aromatic hydrocarbons. Environmental Science and Pollution Research, 2014, 21 (24), pp.13888 - 13897. ⟨10.1007/s11356-014-3116-0⟩. ⟨hal-01451554⟩
148 Consultations
1585 Téléchargements

Altmetric

Partager

Gmail Mastodon Facebook X LinkedIn More