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Poster De Conférence Année : 2016

Randomized blocked design applied for the multicriteria optimization of headspace trap extraction of furan and furfural from sponge cake

Mayela Cepeda Vasquez
David Blumenthal
Valérie Camel
Barbara Rega

Résumé

Furan, a possibly carcinogenic compound to humans, and furfural, a naturally occurring aroma compound, can be produced in heat - processed foods [1,2]. Therefore, their simultaneous determination is important for food safety and quality purposes. Headspace techniques coupled to gas chromatography - mass spectro metr y (G C - M S ) are often used to analyze process - induced compounds. Although headspace trap (H S Trap) extraction has been recently used for furan quantitation in bread crust [3], this technique has not been used for the simultaneous determination of furan and furfural before. This work presents an optimal design of experiments ( O - D O E) approach using random blocks for the multicriteria optimization of H S Trap extraction of furan and furfural from sponge cake for their quantification by G C - M S . A bias related to sample preservation was observed during preliminary tests and eliminated in further assays by considering it as a blocking factor. A tailor - made experimental plan including four instrumental factors (i.e. thermostatting temperature and time, dry purge time, pressurization cycles) and two sample preparation variables (i.e. ratio of water and sample weight [dry basis] and total amount [dry basis]), considering the blocking factor was designed. Response surface models ( P - value <0.0001; R 2 0.974 for a ll mode ls) resulted in the identification o f most linear and so me quadratic terms and a few second order interactions as influencing the extraction of furan, furfural and their internal standards, d4 - furan and d4 - furfura l. Interestingly, one of the samp e preparation variables, namely the ratio of water and samp le weight (dry basis), showed no effect on furfural extraction, while different profiles for furan and d4 - furan were observed regarding this factor. A set of optimal conditions for a H S Trap extraction method was, for the first time, success fully defined by using the optima design of experiments methodology and a desirability function.
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Dates et versions

hal-01449989 , version 1 (03-06-2020)

Identifiants

  • HAL Id : hal-01449989 , version 1
  • PRODINRA : 384864

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Mayela Cepeda Vasquez, David Blumenthal, Valérie Camel, Barbara Rega. Randomized blocked design applied for the multicriteria optimization of headspace trap extraction of furan and furfural from sponge cake. 16. Chemometrics in Analytical Chemistry - CAC 2016, Jun 2016, Barcelone, Spain. , 2016, XVI Chemometrics in Analytical Chemistry. ⟨hal-01449989⟩
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